Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 0.5 and 44.9 nM at MC4 and MC3 respectively) that antagonizes the effects of α-MSH. Suppresses thyrotropin-releasing hormone (TRH) release, attenuates food intake and reduces formalin-induced pain in vivo.

436083-30-6

C69H91N19O16S2

1506.72

JKC 363;JKC363

H2O:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years