MRTX-1719 是有效的PRMT5/MTA复合体选择性抑制剂,其对PRMT5/MTAMTAPDELSDMA 细胞系的IC50值为<10 nM。
产品描述
MRTX-1719 is a potent, first-in-class, selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAP DEL SDMA cells.
Cas No.
2630904-45-7
分子式
C23H18ClFN6O2
分子量
464.88
别名
MRTX-1719
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years