The compound binds and blocks farnesyl diphosphate synthase in the HMG-CoA pathway (IC50 = 460 nM for recombinant human FPPS). It causes macrophage apoptosis and inhibits prenylation and sterol biosynthesis in purified osteoclasts.

129318-43-0

C4H13NNaO7P2

272.09

Alendronate sodium

DMSO:<1 mgml
H2O:≥15mg/mL,with gentle warmingmg
Powder: -20°C for 3 years
In solvent: -80°C for 2 years