PI3K/mTOR Inhibitor-7 (Compound 19i) 是一种有效的PI3K/mTOR双重抑制剂。PI3K/mTOR Inhibitor-7 的效力比阳性对照 gedatolisib 高 4.7 倍（0.3 对 1.4 μM，IC50值）。PI3K/mTOR Inhibitor-7 在 10 μM 时显着抑制 PI3K/Akt/mTOR 信号通路。PI3K/mTOR Inhibitor-7 具有研究癌症疾病的潜力。

PI3K/mTOR Inhibitor-7 (Compound 19i) is a potent and dual inhibitor of PI3K / mTOR. PI3K/mTOR Inhibitor-7 shows 4.7-fold higher potency than the positive control gedatolisib (0.3 vs. 1.4 μM, IC 50 values). PI3K/mTOR Inhibitor-7 significantly suppresses the PI3K/Akt/mTOR signaling pathway at 10 μM. PI3K/mTOR Inhibitor-7 has the potential for the research of cancer diseases [1].

2456295-65-9

C29H33N9O4

571.63

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years