PKM2 activator 3 是一种有效的PKM2激活剂，AC50为 90 nM。PKM2 activator 3 具有良好的 Caco-2 渗透性、低外排比和高微粒体稳定性。PKM2 activator 3 可用于抗癌研究。

PKM2 activator 3 is a potent PKM2 activator with an AC 50 value of 90 nM. PKM2 activator 3 has good Caco-2 permeability, a low efflux ratio and high microsomal stability. PKM2 activator 3 can be used for researching anticancer [1]. (AC 50 : the concentration which gives 50% activation of enzyme.)

PKM2 activator 3 (compound 66) has good Caco-2 permeability, a low efflux ratio (0.84) and high microsomal stability (t 1/2 = 277.2 min in human liver microsomes and 117.5 min in mouse liver microsomes) [1].

1346113-84-5

C15H11ClF2N2O3S

372.77

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years