K114 binds tightly to amyloid fibrils (EC50: 20-30 nM). K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI).

The unusually low buffer fluorescence of K114 is due to self-quenching in sedimentable aggregates or micelles which upon interacting with amyloid fibrils undergo an enhancement in fluorescence intensity and shifts in the excitation and emission spectra [1].

872201-12-2

C22H17BrO2

393.27

K114

DMSO:100 mg/mL (254.28 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years