21-deacetyldeflazacort 是 Deflazacort 的代谢物，它是一种全身性皮质类固醇和泼尼松龙的衍生物。

21-deacetyldeflazacort is a metabolite of Deflazacort, which is a systemic corticosteroid and a derivative of prednisolone.

21-deacetyldeflazacort displaces [3H]dexamethasone from its cytosol receptor sites in rat kidney, thymus and liver in vitro.

21-deacetyldeflazacort inhibited 48-h homologous passive cutaneous anaphylaxis in rats, but had no significant effects on active systemic anaphylaxis in mice, on the Schultz-Dale reaction in the isolated guinea-pig trachea or on compound 48/80-induced histamine release in rat peritoneal mast cells. 21-deacetyldeflazacort inhibited reversed cutaneous anaphylaxis in rats and the Arthus reaction in mice[1].

13649-57-5

C23H29NO5

399.48

21-deacetyldeflazacort

DMSO:65 mg/ml (162.71 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years