Sigma-LIGAND-1 hydrochloride 是一种选择性sigma受体配体，在 DTG 和 PPP 位点的IC50分别为 16 nM，19 nM。Sigma-LIGAND-1 hydrochloride 对多巴胺 D2受体的Ki为 4000 nM。

Sigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand with an IC 50 s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 hydrochloride has a K i of 4000 nM at the dopamine D 2 receptor [1].

Administration of Sigma-LIGAND-1 hydrochloride reverseS amphetamine-induced hyperlocomotion in mice, a behavioral model sensitive to antipsychotic compounds. Sigma-LIGAND-1 hydrochloride and its structural analogues have the potential antipsychotic activity [1].

139652-86-1

C27H34ClNO4

472.02

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years