NF-Κb inhibitor is a synthetic peptide corresponding to the nuclear localization sequence of NF-Κb p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.1It blocks the nuclear import of p105 in cells treated with activators of NF-Κb signaling, including LPS and TNF-α.1In this way, NF-Κb inhibitor blocks gene expression that is regulated by NF-Κb.2,3This peptide is commonly used to evaluate the role of NF-Κb signaling in cellular responses.4,5

NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.1It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.1In this way, NF-κB inhibitor blocks gene expression that is regulated by NF-κB.2,3This peptide is commonly used to evaluate the role of NF-κB signaling in cellular responses.4,5

NF-κB Inhibitor (trifluoroacetate salt)

PBS (pH 7.2):5 mg/mL
DMSO:30 mg/mL
DMF:30 mg/mL
Ethanol:50 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years