The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and colonization-associated surface proteins to the cell wall. SrtA selectively recognizes a C-terminal LPXTG motif. SrtA readily reacts with its native substrate Abz-LPETG-Dap(DNP)-NH2, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges.

TP1634

C41H57N11O14

928

Bacterial Sortase Substrate III, Abz/DNP

H2O:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years