Umibecestat HCl (CNP-520; CNP520), the hydrochloride salt of umibecestat which is a anti-AD (Alzheimer's disease) drug candidate in clinical trials, is a novel and potent beta-secretase (BACE) inhibitor with superior BACE1/BACE2 selectivity and excellent pharmacokinetics. CNP520
reduced significantly Aβ levels in mice and rats in acute and chronic
treatment regimens without any side effects and thus qualified for
Alzheimer's disease prevention studies in the clinic.
纯度:≥98%
CAS:2365306-62-1