| CAS NO: | 66898-62-2 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
Description: Talniflumate (BA -602-06), a prodrug of Niflumic acid, is a potent,orally bioactiveand selective inhibitor of core mucin-synthesizing enzyme GCNT3 (core 2b-1,6 N-acetylglucosaminyltrans-ferase). Talniflumate is a Ca2+-activated Cl- channel (CaCC)
blocker and has to be converted to the active formNiflumic acid in order to exert its effects. Talniflumate can be used as an analgesic and anti-inflammatory
agent in cystic fibrosis mouse model of distal intestinal obstructive
syndrome. References: [1].Hyun-Ji
Kim, et al. Pharmacokinetics of talniflumate, a prodrug of niflumic
acid, following oral administration to man. Archives of Pharmacal
Research volume 19, Article number: 297 (1996) [2].Mollereau,
et al. Agonist and Antagonist Activities on Human NPFF(2) Receptors of
the NPY Ligands GR231118 and BIBP3226. Br J Pharmacol.2001
May;133(1):1-4. [3]. Pharmacokinetic comparison of two formulations of talniflumate 370 mg tablets in healthy Korean volunteers?. Int J Clin Pharmacol Ther. 2017 Jan;55(1):102-108.
纯度：≥98%
CAS：66898-62-2
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