WZ4002-hydroxy is a WZ4002 (InvivoChem Cat#: 203170) analogue or WZ4002 analogue. In which the methoxy group is replaced by hydroxy group. WZ4002 is EGFR inhibitor against EGFR T790M (mutation of the gatekeeper T790 residue) which is detected in 50% of clinically resistant patients to gefitinib or erlotinib. WZ4002 has a basic chemical framework (covalent pyrimidine) which is different from that of other EGFR inhibitors. References:

纯度：≥98%