PF-249, formerly known as PF-06685249, is a beta1-selective AMPK agonist. PF-06685249 is a potent AMPK activator. PF-06685249 exhibited robust activation of AMPK in rat kidneys as well as desirable orally bioavailable absorption, low plasma clearance, and negligible renal clearance in preclinical species.
纯度:≥98%
CAS:1467059-70-6