Phenylbutazone is a compound of research interest as an anti-inflammatory and anti-proliferative agent. Phenylbutazone acts as a potentent anti-inflammatory agent and mediates prostaglandin synthesis. It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). Phenylbutazone may be of interest regarding research into anti-proliferative effects as well. Phenylbutazone is an inhibitor of Cox (cyclooxygenase) that is also a substrate for peroxidation by Cox. References: Knych HK, Stanley SD, Seminoff KN, McKemie DS, Kass PH. Pharmacokinetics of methocarbamol and phenylbutazone in exercised Thoroughbred horses. J Vet Pharmacol Ther. 2016 Feb 29. doi: 10.1111/jvp.12298. [Epub ahead of print] PubMed PMID: 26924025.

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CAS：50-33-9