Ormaplatin is a platinum(IV) analogue with antineoplastic activity. Ormaplatin alkylates DNA, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) References: Tutsch KD, Arzoomanian RZ, Alberti D, Tombes MB, Feierabend C, Robins HI, Spriggs DR, Wilding G. Phase I clinical and pharmacokinetic study of an one-hour infusion of ormaplatin (NSC 363812). Invest New Drugs. 1999;17(1):63-72. PubMed PMID: 10555124.

纯度：≥98%

CAS：62816-98-2