BRD-IN-3 ((R,R)-36n) 是一个强效的P300/CBP 相关因子溴端结构域 (PCAF BRD) 的抑制剂，其IC50 值为 7 nM。BRD-IN-3 也能抑制GCN5 和FALZ。
CAS：2351938-32-2
分子式：C21H25N5O3
分子量：395.45
纯度：98%
存储：Store at -20°C

Background:

BRD-IN-3 ((R,R)-36n) is a highly potent PCAF bromodomain (BRD) inhibitor, with an IC50 of 7 nM. BRD-IN-3 also exhibits activity against GCN5 and FALZ[1]. IC50: PCAF BRD[1].

[1]. Huang L, et al. Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain. J Med Chem. 2019 May 9;62(9):4526-4542.