RIPK-IN-4 是一种有效选择性的、具有良好的口服生物利用度的 RIPK2 抑制剂,IC50 值为 3 nM。
CAS:2141969-56-2
分子式:C18H21FN4O3S
分子量:392.45
纯度:98%
存储:Store at -20°C
Background:
RIPK-IN-4 is a potent and selective RIPK2 inhibitor with excellent oral bioavailability, and has an IC50 of 3 nM[1].
IC50: 3 nM (RIPK2)[1]
[1]. He X, et al. Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett. 2017 Sep 27;8(10):1048-1053.