生物活性
Arbutin (Uva,p-Arbutin)是用于中药(TCM)的糖基化对苯二酚。 熊果苷由于其酪氨酸酶抑制活性而抑制黑色素的形成。
化学数据
目录号 | A10084 |
作用机制 | Inhibitor (抑制剂) |
M. Wt | 272.3 |
Formula | C12H16O7 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 497-76-7 |
Synonyms | Uva, Ursi, p-Arbutin, Hydroquinone β-D-glucopyranoside |
SMILES | C1=CC(=CC=C1O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O |
溶解度
In vitro | DMSO | 49 mg/mL (179.98 mM) |
Water | 49 mg/mL (179.98 mM) |
Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 36.72 mL | 183.62 mL | 367.24 mL |
0.5 mM | 7.34 mL | 36.72 mL | 73.45 mL |
1 mM | 3.67 mL | 18.36 mL | 36.72 mL |
5 mM | 0.73 mL | 3.67 mL | 7.34 mL |
*The above data is based on the productmolecular weight 272.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.