Swinholide A is a natural dimeric dilactone macrolide toxin that causes actin depolymerization in cells.
CAS:95927-67-6
分子式:C78H132O20
分子量:1389.9
纯度:98%
存储:Store at -20°C
Background:
Swinholide A is a natural dimeric dilactone macrolide toxin that causes actin depolymerization in cells. It stabilizes actin dimers and also binds to and severs F-actin filaments. Swinholide A binds to G-actin in a 1:2 molar ratio and decreases the rate of nucleotide exchange in G-actin.