生物活性
Luteolin是PDE4抑制剂、磷酸二酯酶抑制剂和白细胞介素6抑制剂，影响木聚嗪/氯胺酮诱导的小鼠麻醉。Luteolin作为单胺转运蛋白激活剂，是少数证明具有这种性质的化学物质之一。
化学数据
| 目录号 | A10541 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 286.2 |
| Formula | C15H10O6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 491-70-3 |
| Synonyms | 3',4',5,7-Tetrahydroxyflavone, Luteoline, Luteolol |
| SMILES | C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O |
溶解度
| In vitro | DMSO | 55 mg/mL (192.14 mM) |
| Water | Insoluble |
| Ethanol | Warmed: 3 mg/mL (10.48 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 34.94 mL | 174.7 mL | 349.41 mL |
| 0.5 mM | 6.99 mL | 34.94 mL | 69.88 mL |
| 1 mM | 3.49 mL | 17.47 mL | 34.94 mL |
| 5 mM | 0.7 mL | 3.49 mL | 6.99 mL |
*The above data is based on the productmolecular weight 286.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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