| CAS NO: | 56341-08-3 |
| 规格: | 98% |
| 分子量: | 310.7 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
Background:
Mabuterol is an agonist of the β2-adrenergic receptor (β2-AR). It induces relaxation of isolated tracheal muscle in guinea pigs and inhibits bronchoconstriction in a guinea pig model of experimental asthma. Administration of mabuterol decreases blood pressure and increases heart rate in a dose-dependent manner in rats, cats, and dogs. These effects are reversed by the selective β2-AR antagonist ICI 118551 , indicating mabuterol is acting at β2-ARs. At concentrations ≥1 μM, mabuterol acts as a β1-AR antagonist in isolated dog right atria.
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