inhibitor of Ca2+-dependent Cl- channel (CaCC) transmembrane protein 16A (TMEM16A)
CAS:552309-42-9
分子式:C19H20N4O3S2
分子量:416.52
纯度:98%
存储:Store at -20°C
Background:
Transmembrane protein 16A (TMEM16A, also known as anoctamin-1) is a calcium-activated chloride channel (CaCC) with roles in transepithelial anion transport and smooth muscle contraction. T16A(inh)-A01 is an aminophenylthiazole that inhibits transient TMEM16A-mediated chloride currents with an IC50 value of