Extracted?from?Paris yunnanensis Franch. rhizome;Store?the?product?in?sealed,?cool?and?dry?condition
CAS：76296-75-8
分子式：C51H84O22
分子量：1049.2
纯度：98%
存储：Store at -20°C

Background:

Polyphyllin G is isolated from the rhizomes of Paris yunnanensis, with antimicrobial and anticancer activity. Polyphyllin G prevents the growth of both Gram-positive and Gram-negative bacteria with minimum inhibitory concentrations (MICs)[1].Polyphyllin G induces apoptosis dependent on the activations of caspase-8, -3, and -9, induces autophagy[2].

参考文献:
[1]. Cai X, et al. Polyphyllin G exhibits antimicrobial activity and exerts anticancer effects on human oral cancer OECM-1 cells by triggering G2/M cell cycle arrest by inactivating cdc25C-cdc2. Arch Biochem Biophys. 2018 Apr 15;644:93-99.
[2]. Hsieh MJ, et al. Polyphyllin G induces apoptosis and autophagy cell death in human oral cancer cells. Phytomedicine. 2016 Dec 1;23(13):1545-1554.