The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase mediates the rate-limiting step in cholesterol synthesis, converting HMG-CoA to mevalonate.
CAS:34695-32-4
分子式:C6H8O4
分子量:144.1
纯度:98%
存储:Store at -20°C
Background:
The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase mediates the rate-limiting step in cholesterol synthesis, converting HMG-CoA to mevalonate. 3-hydroxy-3-Methylglutaric anhydride is a precursor that is used in the synthesis of HMG-CoA. It has also been used in the synthesis of 3-alkyl-3-hydroxyglutaric acids that act as inhibitors of HMG-CoA reductase.