4-Hydroxyestradiol
4-Hydroxyestradiol, an metabolite of estradiol, forms adducts with adenine (3) and guanine (N7) by depurinating sites in DNA of cultured human breast epithelial cells.
CAS:5976-61-4
分子式: C18H24O3
分子量:288.38
纯度:98%
存储:Store at -20°C
Background:
<p>4-Hydroxyestradiol, an metabolite of estradiol, forms adducts with adenine (N<sup>3</sup>) and guanine (N<sup>7</sup>) by depurinating sites in DNA of cultured human breast epithelial cells. This effect may play an important role in malignant transformation of these cells.</p>