Extracted from Glycine max(L.)Merr.;Suitability:Chloroform,benzene,ethyl acetate,pyridine,ethanol,acetone;Store the product in sealed,cool and dry condition
CAS：83-48-7
分子式：C29H48O
分子量：412.69
纯度：98%
存储：Store at -20°C

Background:

Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.

Preincubation of Stigmasterol to IL-1beta-treated cells shows signi?cant reduction of MMP-3 mRNA in human and mouse, MMP-3 protein in mouse, MMP-13 mRNA in mouse and human, ADAMTS-4 mRNA in human, PGE2 protein in human and mouse. Stigmasterol is also capable of counteracting the IL-1beta-induced NF-κB pathway[1].

参考文献:
[1]. Gabay O, et al. Stigmasterol: a phytosterol with potential anti-osteoarthritic properties. Osteoarthritis Cartilage. 2010 Jan;18(1):106-16.