BI-4916 是 BI-4924 的前药。BI-4924 是一种 NADH/NAD+- 竞争性的磷酸甘油酸脱氢酶 (PHGDH) 抑制剂。。
CAS：2244451-48-5
分子式：C23H24Cl2N2O6S
分子量：527.42
纯度：98%
存储：Store at -20°C

Background:

BI-4916 is a prodrug of BI-4924. BI-4924 is a NADH/NAD+-competitive PHGDH inhibitor[1].

[1]. Weinstabl H, et al. Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis. J Med Chem. 2019 Jul 31.