| CAS NO: | 91183-98-1 |
| 包装: | 5mg |
| 规格: | 98% |
| 市场价: | 445元 |
| 分子量: | 651.32 |
Background:
UDP-GlcNAc Disodium Salt is a donor substrate of O-GlcNAc transferase (OGT).
OGT is a nucleocytoplasmic glycosyltransferase (uridine diphospho-N--acetylglucosamine:polypeptide β-N-acetylglucosaminyltransferase or O-GlcNAc transferase) assigned to the GT41 family in the CAZY (Carbohydrate-Active enZYme) database. Using UDP-GlcNAc Disodium Salt (UDP-GlcNAc) as the donor substrate, this enzyme modifies thousands of proteins by adding a unique N-acetylglucosamine residue onto acceptor substrates mainly confined within cytosol and nucleus[1].
[1]. Lefebvre T, et al. Antibodies and activity measurements for the detection of O-GlcNAc transferase and assay of its substrate, UDP-GlcNAc. Methods Mol Biol. 2013;1022:147-59.
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