Osteoclast-mediated bone resorption inhibitor
CAS：129318-43-0
分子式：C4H12NNaO7P2
分子量：271.08
纯度：98%
存储：Store at -20°C

Background:

Osteoclast-mediated bone resorption inhibitor. Binds and blocks farnesyl diphosphate synthase (FPPS) in the HMG-CoA pathway (IC50 = 460 nM for recombinant human FPPS); causes macrophage apoptosis. Inhibits prenylation and sterol biosynthesis in purified osteoclasts.