I-CBP112是一种特异性和有效的乙酰-赖氨酸竞争性蛋白-蛋白相互作用抑制剂，靶向CBP/p300溴结构域,在白血病细胞中的IC50值为5.5±1.1μM。
CAS：1640282-31-0
分子式：C27H36N2O5
分子量：468.59
纯度：98%
存储：Store at -20°C

Background:

I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor, that targets the CBP/p300 bromodomains.

I-CBP112 significantly enhances acetylation by p300 at the histone H3K18 and H3K23 sites. I-CBP112 stimulated H3K18ac by