Inupadenant (EOS-850) 是一种具有口服活性的，高选择性 A2A 受体拮抗剂。Inupadenant 不能透过血脑屏障。Inupadenant 具有抗肿瘤活性。
货号:ajcx34870
CAS:2246607-08-7
分子式:C25H26F2N8O4S2
分子量：604.65
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Inupadenant is an orally active, highly selective A2A receptor antagonist. Inupadenant is not brain-penetrant. Inupadenant has potent anti-tumor activity[1].

[1]. Laurence Buisseret, et al. Phase 1 trial of the adenosine A2Areceptor antagonist inupadenant (EOS-850): Update on tolerability, and antitumor activity potentially associated with the expression of the A2A receptor within the tumor. Journal of Clinical Oncology. Volume 39, Issue 15_suppl.