USP30 inhibitor 18 是一种选择性 USP30 抑制剂,IC50 为 0.02 μM。USP30 inhibitor 18 增加蛋白质泛素化并加速线粒体自噬。
货号:ajcx33668
CAS:2242582-40-5
分子式:C26H28FN3O4S
分子量:497.58
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
USP30 inhibitor 18 is a selective USP30 inhibitor with an IC50 of 0.02 μM. USP30 inhibitor 18 increases protein ubiquitination and accelerates mitophagy[1].
[1]. Arthur F Kluge, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg Med Chem Lett. 2018 Aug 15;28(15):2655-2659.