Pomalidomide-C7-COOH是一种合成的E3连接酶配体-linker偶联物,是PROTACBCL-XL降解剂合成的中间体。
货号:ajcx31324
CAS:2225940-51-0
分子式:C21H25N3O6
分子量:415.44
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders[1].
[1]. Zhang X, et, al. Discovery of PROTAC BCL-X L degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15; 192: 112186.