3-O-Methyldopa(3-Methoxy-L-tyrosine)是一种由邻苯二酚-O-甲基转移酶(COMT)形成的L-DOPA代谢物。3-O-Methyldopa竞争性抑制L-DOPA和多巴胺(dopamine)的药效学。
货号:ajcx30008
CAS:300-48-1
分子式:C10H13NO4
分子量：211.21
溶解度:H2O: 16.67 mg/mL (78.93 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine[1].

[1]. Masato Asanuma, et al. 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of L-DOPA. BMC Neurosci. 2016 Jul 25;17(1):52.