Albiglutide TFA 是一种胰高血糖素样肽 GLP-1 模拟物，是长效 GLP-1 受体激动剂，用于治疗治疗 2 型糖尿病 (T2DM)。Albiglutide TFA 是由抗 DPP-4 的 GLP-1 二聚体与人白蛋白的基因融合产生的。
货号:ajcx29100
CAS:N/A
分子式:C150H225F3N40O47
分子量：3397.63
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Albiglutide TFA, a glucagon-like peptide (GLP)-1 mimetic, is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM). Albiglutide TFA is generated by the genetic fusion of a DPP-4-resistant GLP-1 dimer to human albumin[1][2].

[1]. Matthews JE, et al. Pharmacodynamics, pharmacokinetics, safety, and tolerability of albiglutide, a long-acting glucagon-like peptide-1 mimetic, in patients with type 2 diabetes. J Clin Endocrinol Metab. 2008 Dec;93(12):4810-7. [2]. Blair HA, et al. Albiglutide: a review of its use in patients with type 2 diabetes mellitus. Drugs. 2015 Apr;75(6):651-63.