An OGA inhibitor
货号:ajcx25266
CAS:179030-22-9
分子式:C8H13NO4S
分子量：219.3
溶解度:DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 5 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

NAG-thiazoline is an inhibitor of O-GlcNAcase (OGA; K_i= 180 nM).¹It is active againstV. campbellii(MIC = 0.5 µM).²

1.Macauley, M.S., and Vocadlo, D.J.Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcaseBiochim. Biophys. Acta1800(2)107-121(2010) 2.Meekrathok, P., Stubbs, K.A., Aunkham, A., et al.NAG-thiazoline is a potent inhibitor of the Vibrio campbellii GH20 β-N-AcetylglucosaminidaseFEBS J.287(22)4982-4995(2020)