An NRP-1/VEGF-A interaction inhibitor
货号:ajcx25166
CAS:1210360-87-4
分子式:C11H9N3O3
分子量：231.2
溶解度:DMF: insol,DMSO: 10 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.¹It inhibits the interaction by 43% when used at a concentration of 12.5 µM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.

1.Perez-Miller, S., Patek, M., Moutal, A., et al.In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike proteinbioRxiv308783(2020)