Dehydrotrametenolic acid 是从茯苓 (Poria cocos) 的菌核中分离的甾醇。Dehydrotrametenolic acid 通过 caspase-3 途径诱导细胞凋亡。Dehydrotrametenolic acid 具有抗肿瘤活性，抗炎，抗糖尿病作用。
货号:ajcx14798
CAS:6879-05-6
分子式:C31H48O3
分子量：468.71
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects[1].

Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed cells with a GI50 value of 40 μM[1].

[1]. Kang HM, et al. Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed rat2 cells and induces apoptosis through caspase-3 pathway. Life Sci. 2006 Jan 2;78(6):607-13.