A PPARα agonist
货号:ajcx22040
CAS:2376590-40-6
分子式:C22H20FNO3
分子量：365.4
溶解度:DMF: 20mg/mL,DMF:PBS (pH 7.2) (1:2): 0.3mg/mL,DMSO: 5mg/mL,Ethanol: 12mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CAY10767 is an agonist of peroxisome proliferator-activated receptor α (PPARα; EC₅₀= 37 nM in a reporter assay).¹It is greater than 2,700-fold selective for PPARα over PPARγ or PPARδ.

1.Dou, X., Nath, D., Shin, H., et al.Evolution of a 4?benzyloxy-benzylamino chemotype to provide efficacious, potent, and isoform selective PPARα agonists as leads for retinal disordersJ. Med. Chem.63(6)2854-2876(2020)