JWH 251 is discontinued (DEA controlled substance). This product is a cannabimimetic indole that shows a high affinity for the central cannabinoid (CB1) receptor with a Ki of 29 nM and a comparatively modest affinity for the peripheral cannabinoid (CB2) receptor (Ki = 146 nM). JWH 251 stimulates GTPγS binding of CB1 and CB2 receptors with EC50 of 29 and 8.3 nM, respectively. References: Gol E, Cok I. Assessment of types of synthetic cannabinoids in narcotic cases assessed by the Council of Forensic Medicine between 2011-2015, Ankara, Turkey. Forensic Sci Int. 2017 Nov;280:124-129. doi: 10.1016/j.forsciint.2017.09.017. Epub 2017 Oct 4. PubMed PMID: 29028489.

纯度：≥98%

CAS：864445-39-6