T-2007, formerly known as DPB and 5,5-Diphenylbarbituric acid, is an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist and gamma-aminobutyric acid (GABA) receptor agonist potentially for the treatment of epilepsy. T2007 and its analogues upregulates CYP3A4 and MDR1. T-2007 depressed both the degree and the duration of posttetanic potentiation (PTP) in a dose-dependent manner. References: Fan J, Maeng HJ, Du Y, Kwan D, Pang KS. Transport of 5,5-diphenylbarbituric acid and its precursors and their effect on P-gp, MRP2 and CYP3A4 in Caco-2 and LS180 cells. Eur J Pharm Sci. 2011 Jan 18;42(1-2):19-29. doi: 10.1016/j.ejps.2010.10.001. PubMed PMID: 20955791.

纯度：≥98%

CAS：21914-07-8