TriN2755 is a synthetic triazene analogue with antineoplastic activity. Upon metabolic activation via N-demethylation, TriN2755 is converted into highly reactive carbocations that can alkylate DNA and other macromolecules, thereby resulting in DNA cross links, inhibiting DNA replication and repair, and subsequently inducing apoptosis. This agent has high hydrophilicity and photostability and shows a favorable toxicity profile over the other triazenes. References: Athanasiadi I, Geigy C, Hilger RA, Meier V, Rohrer Bley C. Safety, tolerability and pharmacokinetic properties of the novel triazene TriN 2755 in tumour bearing dogs - a phase I study(+). Vet Comp Oncol. 2015 Feb 16. doi: 10.1111/vco.12145. [Epub ahead of print] PubMed PMID: 25689225.

纯度：≥98%

CAS：1095806-02-2