DQP-1105 (DQP1105) is a novel, potent, non-competitive and negative allosteric modulator of the GluN2C/D NMDA receptor with potential to be used for Neuroscience applications. It exhibits over 50-fold selectivity for GluN2D- and GluN2C-containing receptors over GluN2B-, GluK2-, GluA1- and GluN2A-containing receptors (IC50 values are 2.7, 8.5, 121, 153, 198 and 206 μM, respectively). It reduces frequency of channel opening.

纯度：≥98%

CAS：380560-89-4