Description: 5-hydroxymethyl tolterodine (also known as Desfesoterodine, PNU 200577, 5-HMT, 5-HM) is a novel muscarinic receptor antagonist with Kb of 0.84 nM. It is a major pharmacologically active metabolite of tolterodine. 5-hydroxymethyl tolterodine produces a competitive and concentration-dependent inhibition of carbachol-induced contraction of guinea-pig isolated urinary bladder strips. 5-hydroxymethyl tolterodine antagotizes muscarinic receptors with a pA2 of 9.1.

References: Pharmacol Toxicol. 1997 Oct;81(4):169-72.

Related CAS #: 380636-50-0 (fumarate) 207679-81-0 (free base)

纯度：≥98%