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Spinosad
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Spinosad图片
CAS NO:168316-95-8
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
多杀菌素是一种多杀菌素 A 和 D 的混合物，被称为土壤放线菌 (Saccharopolyspora spinosa) 的发酵产物，是一种具有更广泛作用谱的生物神经毒性杀虫剂。
Cas No.168316-95-8
Canonical SMILESCN(C)[C@H]1CC[C@@](O[C@H]([C@@H](C)C2=O)CCC[C@H](CC)OC(C[C@]3([H])C2=C[C@]4([H])[C@@]3([H])C=C[C@@]5([H])[C@@]4([H])C[C@H](O[C@]6([H])O[C@@H](C)[C@H](OC)[C@@H](OC)[C@H]6OC)C5)=O)([H])O[C@@H]1C.CN(C)[C@H]7CC[C@@](O[C@H]([C@@H](C)C8=O)CCC[C@H](CC)OC(C[C@]9([H])C8=C[C@]%10([H])[C@@]9([H])C=C(C)[C@@]%11([H])[C@@]%10([H])C[C@H](O[C@]%12([H])O[C@@H](C)[C@H](OC)[C@@H](OC)[C@H]%12OC)C%11)=O)([H])O[C@@H]7C
分子式C83H132N2O20
分子量1478
溶解度Ethanol: 1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Spinosad is a naturally-occurring insecticide found in the the soil bacteriumS. spinosa.1It is a mixture of the macrocyclic lactones spinosyn A and spinosyn D , which act as agonists of insect nicotinic acetylcholinesterase receptors (nAChRs). Oral administration of spinosad induces toxicity in fruit flies includingC. capitata, B. curcurbitae, andB. dorsalis(LC50s = 2.8-4.2, 4.3-5.5, and 3.1-3.3 µg/ml, respectively) but has low toxicity in vertebrates.2,3,4It also inhibits canine P-glycoprotein (P-gp; IC50= 0.2 µg/ml).5Formulations containing spinosad have been used in the agricultural and veterinary control of insects.

1.Vo, D.T., Hsu, W.H., Abu-Basha, E.A., et al.Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animalsJ. Vet. Pharmacol. Ther.33(4)315-322(2010) 2.Stark, J.D., Vargas, R., and Miller, N.Toxicity of spinosad in protein bait to three economically important tephritid fruit fly species (Diptera: Tephritidae) and their parasitoids (Hymenoptera: Braconidae).J. Econ. Entomol.97(3)911-915(2004) 3.SÁnchez-Bayo, F.Insecticides mode of action in relation to their toxicity to non-target organismsJ. Environ. Anal. Toxicol.S4:002(2012) 4.Amaral, T.S., Carvalho, T.F., Silva, M.C., et al.Short-term effects of a spinosyn's family insecticide on energy metabolism and liver morphology in frugivorous bats Artibeus lituratus (Olfers, 1818)Braz. J. Biol.72(2)299-304(2012) 5.Schrickx, J.A.Spinosad is a potent inhibitor of canine P-glycoproteinVet. J.200(1)195-196(2014)