| CAS NO: | 38339-02-5 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 38339-02-5 |
| Canonical SMILES | O=S(O)(OC1=CC=C(CCN)C=C1O)=O |
| 分子式 | C8H11NO5S |
| 分子量 | 233.2 |
| 溶解度 | DMSO: slightly |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Dopamine 4-O-sulfate is an inactive metabolite of the catecholamine dopamine .1,2It is formed from dopamine by the sulfotransferase (SULT) isoform SULT1A3.3Dopamine 4-O-sulfate is found at lower levels in the brain and circulation than dopamine 3-O-sulfate .1,3 1.Suominen, T., Uutela, P., Ketola, R.A., et al.Determination of serotonin and dopamine metabolites in human brain microdialysis and cerebrospinal fluid samples by UPLC-MS/MS: Discovery of intact glucuronide and sulfate conjugatesPLoS One8(6)e68007(2013) 2.Kyncl, J.J., Buckner, S.A., Brondyk, H., et al.Adrenergic and dopaminergic properties of dopamine sulfoconjugatesJ. Cardiovasc. Pharmacol.7(6)1198-1204(1985) 3.ItÄaho, K., Alakurtti, S., Yli-Kauhaluoma, J., et al.Regioselective sulfonation of dopamine by SULT1A3 in vitro provides a molecular explanation for the preponderance of dopamine-3-O-sulfate in human blood circulationBiochem. Pharmacol.74(3)504-510(2007) |
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