INCB-086550 (INCB-086550) is a novel, potent and selective small molecule PD-1/PD-L1 Inhibitor based on the biphenyl scaffold core structure first disclosed by BMS company. Blocking the activity of the programmed cell death protein 1 (PD-1) inhibitory receptor with therapeutic antibodies against either the ligand (PD-L1) or PD-1 itself has proven to be an effective treatment modality for multiple cancers. Contrasting with antibodies, small molecules could demonstrate increased tissue penetration, distinct pharmacology, and potentially enhanced antitumor activity.

纯度：≥98%

CAS：2230911-59-6