| CAS NO: | 939-19-5 |
| 包装: | 5 g |
| 市场价: | 3311元 |
| Cas No. | 939-19-5 |
| 别名 | 3-羟基香豆素 |
| Canonical SMILES | O=C1OC2=C(C=C1O)C=CC=C2 |
| 分子式 | C9H6O3 |
| 分子量 | 162.1 |
| 溶解度 | DMF: 15 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml,DMSO: 10 mg/ml,Ethanol: 1 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 3-Hydroxycoumarin is a coumarin that has been found inA. reinwardtiiand has diverse biological activities.1,2,3It inhibits 15-lipoxygenase-1 (15-LO-1; IC50= 9.5 µM).13-hydroxycoumarin scavenges DPPH radicals in a cell-free assay (IC50= 0.61 mM) and inhibits lipid peroxidationin vitro(IC50= 69.07 mM).2It is protective against UVB-induced embryotoxicity in sea urchins (E. lucunter).3 1.Alavi, S.J., Sadeghian, H., Seyedi, S.M., et al.A novel class of human 15-LOX-1 inhibitors based on 3-hydroxycoumarinChem. Biol. Drug Des.91(6)1125-1132(2017) 2.Rattanapan, J., Sichaem, J., and Tip-pyang, S.Chemical constituents and antioxidant activity from the stems of Alyxia reinwardtiiRec. Nat. Prod.6(3)288-291(2012) 3.de Araujo Leite, J.C., de Castro, T.M.X., Barbosa-Filho, J.M., et al.Photoprotective effect of coumarin and 3-hydroxycoumarin in sea urchin gametes and embryonic cellsJ. Photochem. Photobiol. B Biol.14644-51(2015) |
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