Misoprostol acid D5

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Misoprostol acid D5

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	1337917-44-8
包装:	1mg
市场价:	7020元

产品介绍

MisoprostolacidD5是Misoprostolacid的氘代物。Misoprostolacid是一种Misoprostol的活性代谢物。Misoprostol是前列腺素E1(PGE1)的合成类似物，被广泛吸收，口服后迅速在胃肠道中转化成Misoprostolacid。Misoprostol可用于非甾体类抗炎药诱发的(NSAID)胃溃疡，还可用于引产的研究。

Cas No.	1337917-44-8
Canonical SMILES	O[C@H]1[C@@H]([C@H](C(C1)=O)CCCCCCC(O)=O)/C=C/CC(C([2H])([2H])[2H])(O)C([2H])([2H])CCC
分子式	C₂₁H₃₁D₅O₅
分子量	373.54
溶解度	DMF: >100 mg/ml,DMSO: >50 mg/ml,Ethanol: >50 mg/ml,PBS pH 7.2: 1 mg/ml
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Misoprostol acid D5 is deuterium labeled Misoprostol acid. Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2]. [1]. Vijaya Bharathi D, et al. Development and validation of highly sensitive method for determination of misoprostol free acid in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry: application to a clinical pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Sep 15;879(26):2827-33. [2]. Schmidt-Hansen M, et al. Simultaneous compared to interval administration of mifepristone and misoprostol for medical abortion up to 10+0 weeks' gestation: a systematic review with meta-analyses. BMJ Sex Reprod Health. 2020 Feb 20. pii: bmjsrh-2019-200448.